By Jerry M. Rice, Charles H. Frith (auth.), Robert Langenbach, Stephen Nesnow, Jerry M. Rice (eds.)
The Symposium on Organ and Species Specificity in Chemical Carcinogenesis was once held March 1981 in Raleigh, North Carolina. Dr. James Miller concluded this Symposium with those comments: "Without a doubt we all could agree this has been a really winning symposium in illustrating a truly wide selection of chemical, stereochemical, biochemical, metabolic, molecular, and organic elements in chemical carcinogenesis. i feel it's noteworthy that a few of the discussions have handled pharmacodynamic, or toxicodynamic, elements that may impression the organic actions of the tremendous wide selection of constructions that we elect to name chemical cancer causing agents. I truly wish that when this symposium each person the following will observe the very nice want we've got for additional details on those brokers within the species we profess to be operating for, the human species. We badly want an enough information base on human organs, human tissues, human cells, human subcellular arrangements, and human physique fluids. i don't believe we will be able to depend on extrapolations of information on chemical carcinogenesis from experimental animals to people, irrespective of how subtle or believable those extrapolations could appear, until eventually we all know way more approximately chemical carcinogenesis in people. Now, i might wish to upload a a bit own word. As lots of you recognize, my spouse and i've shared a joint profession of a few forty years during this box, and i might prefer to emphasize in those final comments the issue of youth.