Annual Reports in Medicinal Chemistry, 2 by C K Cain

By C K Cain



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Collins, Ed. , L e a and F e b i g e r , Philadelphia, 1966, pp. 428-434. 55. N. W. , "The Application of Neuroleptanalgesia", P e r g a m o n P r e s s , New York, 1966. 56. M. G e m p e r l e , Ed. , " F o r t s c h r i t t e d e r Neuroleptanalgesie", SpringerVerlag, B e r l i n , Heidelberg, New York, 1966. 57. W. E. Field, J . Yelnosky, J. Mundy, J. Mitchell, J. A m . Vet. Med. , 149, 896 (1966). - - C h a p t e r 4 . A n a l g e t i c s --- S t r o n g and Weak Louis S H a r r i s and W i l l i a m L.

4D 5, - F r o m a survey of the clinical experience with chlorphentermine to date, it a p p e a r s that at effective anorectic doses t h e r e i s a low but about equal incidence of both d e p r e s s a n t and stimulant CNS side effects. 7* The N-ethylcarbamate of chlorphentermine (Ib, cloferex) i s r e o r t ed to be a l e s s toxic, longer acting compound than the parent base. , and R" w a s H Ano r exig ens Chap. 5 R” Q ~ H ~ ~ H - NI - c H ~ -Rl R I1 CH3 R a. b. H H,C1,CF3 Poos R’ phenyl phenyl, subst.

210, 329 (1966). 37. Schally, Acta Endocrinol. 2, 391 (1966). 38. George, Brain Research 2, 361 (1966). 39. Ward-McQuaid, Brit. J. Anaes. 38, 345 (1966). 40. Rogers, Clin. Pharm. Therap. 1,740 (1966). 41. Filler, Obstet. Gynecol. 28, 224 (1966). 42. Hopper, Clin. Pharm, Therap. L, 447 (1966). 43. Rusy, Anesthesia and Analgesia 45, 176 (1966). 44. McClane, Clin. Pharm. Therap. 7, 455 (1966). 45. Freedman, Personal communications. 46. Hyman, Proc. SOC. Exp. Biol. Med. 118, 763 (1965). 47. J. Harris, J.

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