African Swine Fever Virus: Bluetongue Virus by William R. Hess, Peter G. Howell, Daniel W. Verwoerd

By William R. Hess, Peter G. Howell, Daniel W. Verwoerd

Bluetongue could be defined as an acute insect borne illness of ruminants, manifested clinically in sheep via a catarrhal irritation of the mucous mem­ branes of the digestive and breathing platforms and linked to degenerative alterations within the skeletal musculature. The profound emaciation and weak point which keep on with the intense ailment are liable for a chronic convalescence and for severe financial losses because of reduced productiveness. II. historic throughout the early colonisation of Africa, vulnerable Merino and different eu breeds of sheep have been brought into the Cape, before everything by way of the Dutch East India corporation among 1652 and 1785 and back later in 1870. A document of the farm animals and Sheep ailments fee (1876) files the looks of a significant febrile ailment among those imported sheep within which either morbidity and mortality was once excessive (cited by way of HENNING, 1949). HuTCHEON (1881) gave this illness the identify of "Fever" or "Epizootic Catarrh", that allows you to distinguish it from different medical stipulations of an analogous nature encountered among sheep. within the first com­ prehensive description of this scientific syndrome and its epizootiology HuTCHEON (1902) stated it as "Malarial Catarrhal Fever of Sheep", a designation which used to be evidently prompted by means of the improper trust that an intracorpuscular parasite used to be the first reason for the affliction. extra systematic experiences have been performed by way of SPREULL (1902; 1905), who endeavoured to immunize sheep via the simultaneous inoculation of immune serum and infective blood.

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In both suckling and 3 to 4-week-old mice the first evidence of multiplication was found approximately 8 to 12 hours after injection and was considered to be the time taken for a single multiplication cycle of the virus in mouse brain tissue. SvEHAG (1962) studied the multiplication of the 180th egg passage of the California BT 8 strain in mice. In this study it was shown that the relationship between the age of the mouse and its susceptibility was influenced by the mouse passage level of the virus used.

PARKER: Evidence for the type of nucleic acid in African swine fever virus. Arch. ges. Virusforsch. 19, 289-304 (1966). , and R. D. FERRIS: Research in tissue culture: African swine fever. East Afr. vet. Res. Org. An. Rep. p. 28 (1956-1957). , and J. PARKER: The stability of African swine fever virus with particular reference to heat and pH inactivation. Arch. ges. Virusforsch. 21, 383-402 (1967). , J. PARKER, and M. A. PIERCE: African swine fever virus in ticks (ornithodoros moubata, Murray) collected from animal burrows in Tanzania.

B. Essential Clinical Features . . . . . . . . . . . . . . . . . . . . C. Pathology . . . . . . . . . . . . . . . . . . . . . . . . . . . 1. Macroscopic Pathology . . . . . . . . . . . . . . . . . . . . 2. Histopathology. . . . . . . . . . . . . . . . . . . . . . . . 3. Clinical Pathology . . . . . . . . . . . . . . . . .

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