Advances in Bioengineering by Pier Andrea Serra

By Pier Andrea Serra

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Pulsed plasma deposition of allyla‐ mine on polysiloxane: a stable surface for neuronal cell adhesion. Journal of neuro‐ science methods 2000;98(2) 135-144. [87] Puleo D A, Kissling R A, Sheu M S. A technique to immobilize bioactive proteins, in‐ cluding bone morphogenetic protein-4 (BMP-4), on titanium alloy. Biomaterials 2002;23(9) 2079-2087. [88] Pu F R, Williams R L, Markkula T K, Hunt J A. Effects of plasma treated PET and PTFE on expression of adhesion molecules by human endothelial cells in vitro.

Characterization techniques Since the surface of an implant will be readily in contact with the biological environment, the surface characteristics of a biomaterial will have a major influence on the cell-material interactions. These characteristics should be analyzed and studied in order to correlate them with the material biocompatibility and thus try to improve it by changing them. In order to evaluate the effect of plasma treatments on the surfaces, physical and chemical characterizations are performed using different techniques, such as: water contact angle measurement (WCA), Fourier-transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and scanning electron microscopy (SEM).

Journal of Biomedical Materials Research 2002;59(4) 632–638. 5772/59691 [46] Dhayal M, Alexander M R, Bradley J W. The surface chemistry resulting from lowpressure plasma treatment of polystyrene: the effect of residual vessel bound oxygen. Applied surface science 2006;252(22) 7957-7963. [47] Hamerli P, Weigel Th, Groth Th, Paul D. Enhanced tissue-compatibility of polyethy‐ lenterephtalat membranes by plasma aminofunctionalisation. Surface and coatings technology 2003;174-175 574-578. [48] Ortiz-Magán A B, Pastor-Blas M M, Ferrándiz-Gómez T P, Morant-Zacarés C, Mar‐ tín-Martínez J M.

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